Canine distemper virus ISCOMs induce protection in harbour seals (Phoca vitulina) against phocid distemper but still allow subsequent infection with phocid distemper virus-1
نویسندگان
چکیده
منابع مشابه
Canine distemper virus (CDV) immune-stimulating complexes (Iscoms), but not measles virus iscoms, protect dogs against CDV infection.
The potential of immune-stimulating complexes (iscoms), a novel form of antigenic presentation, for the induction of protective immunity against morbillivirus infection was shown by immunizing dogs with canine distemper virus (CDV) iscoms, which contained the fusion (F) protein and a minor amount of the haemagglutinin of the virus. The immunized dogs developed CDV-neutralizing antibodies but, i...
متن کاملRound table on morbilliviruses in marine mammals.
Since 1988 morbilliviruses have been increasingly recognized and held responsible for mass mortality amongst harbour seals (Phoca vitulina) and other seal species. Virus isolations and characterization proved that morbilliviruses from seals in Northwest Europe were genetically distinct from other known members of this group including canine distemper virus (CDV), rinderpest virus, peste des pet...
متن کاملSimultaneous canine distemper encephalitis and canine parvovirus infection with distemper..
Simultaneous infection of canine distemper virus and canine parvovirus associated with distemper myocardial degeneration and necrosis is described in a pup. The dog demonstrated myoclonus, nystagmus, enamel hypoplasia, abdominal pustules, and bilateral corneal ulceration clinically. Demyelinating encephalitis, myocardial degeneration and necrosis with mineralization, and necrosis, hemorrhage an...
متن کاملMolecular and Immunological Investigation of Canine Distemper Virus (CDV) and Its Co- Infection with Canine Parainfluenza Virus Type 2
Background and Objective: Canine distemper (CD) is a highly transmissible serious disease of carnivores. Distemper virus has immunosuppression effects, which, in turn, could lead to opportunistic infections. The present study was performed to detect CDV by the genomic and immunological methods and investigate its co- infection with canine parainfluenza virus type 2 (CPiV-2). Materials and Meth...
متن کاملA Mechanistic Model to Describe the Spread of Phocid Distemper Virus
REPORTRAPPORT A mechanistic model to describe the spread of phocid distemper virus A. Abstract 1. The 1988 epizootic among seals in N.W. Europe led to the death of more than half of the population. Several researchers have tted data from the epidemic with the Kermack and McKendrick model for disease spread. 2. We argue that for animals living in herds or colonies, like seals, the mutual contact...
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ژورنال
عنوان ژورنال: Vaccine
سال: 1992
ISSN: 0264-410X
DOI: 10.1016/0264-410x(92)90390-6